Methylene Blue

Methylene Blue Benefits:

• Improves mitochondrial function and ATP synthesis, resulting in increased energy levels.
• Reduces oxidative stress.
• Exerts a neuroprotective effect, which can be used to reduce factors predisposing to the development of Alzheimer's and Parkinson's.
• Improves memory, nootropic effect.
• Microdoses used for anti-aging applications.
• Improves skin quality and hydration, accelerates wound healing.
• Potent antioxidant effect.

What is methylene blue used for today?

Methylene blue is still used in diagnostic procedures to identify abnormal cells. It features a characteristic blue color and is used to treat various conditions, such as methemoglobinemia. MB is most commonly prescribed to treat methemoglobinemia, and occasionally malaria or cyanide poisoning.

Is methylene blue harmful?

In low doses, methylene blue is not dangerous for most people. Individuals taking certain antidepressants, opioids, or antihistamines must not use MB. Pregnant women and individuals with G6PD deficiency should also avoid MB. G6PD deficiency is the most common enzymatic disorder in humans. It is caused by a deficiency of glucose-6-phosphate dehydrogenase, an enzyme present in red blood cells. The most common symptoms are jaundice and hemolytic anemia.

1. Aging
   Methylene blue is beneficial for the skin. MB enhances mitochondrial function and reduces oxidative stress—both of which independently improve the skin's appearance. MB has even been utilized in the management of psoriasis, an autoimmune disease. By boosting collagen and elastin production, methylene blue lends the skin a more youthful appearance. (source)
2. Depression
   Methylene blue can exert a "strong" antidepressant effect. This is because it can increase levels of norepinephrine, serotonin, and dopamine in the brain, inhibiting the breakdown of these neurotransmitters. MB may also help regulate anxiety and bipolar disorder, which are closely linked to depression. It is advised not to take MB concurrently with other antidepressants. (Sources 1, 2)
3. Lyme disease and co-infections
   While most patients with Lyme disease recover after 2–4 weeks of antibiotics, up to 20% do not recover as quickly. Methylene blue is a potential alternative for individuals in whom antibiotic therapy has failed. In laboratory settings, methylene blue has effectively eliminated antibiotic-resistant Lyme bacteria. Combining methylene blue with certain antibiotics enhances their efficacy against Lyme disease. Studies have also demonstrated that combining methylene blue with antibiotics is more effective than antibiotics alone in treating Bartonella infections. (Sources 1, 2)
4. Alzheimer's Disease, Parkinson's Disease
   Methylene blue can help prevent Alzheimer's disease, Parkinson's disease, and mild cognitive impairment. MB reduces oxidative damage to brain cells—a major contributor to neurodegenerative conditions such as Alzheimer's and Parkinson's. Numerous studies demonstrate that MB is "a promising neuroprotective intervention for both motor and non-motor" symptoms of Parkinson's disease. While MB is not a panacea for neurotoxicity and neurodegenerative diseases, methylene blue boasts decades of documented neuroprotective benefits. (Sources 1, 2)
5. Methemoglobinemia
   Is a blood disorder that can cause headaches, dizziness, nausea, or skin discoloration. Methylene blue is an FDA-approved medication for this predominantly genetic condition, which can give blood a chocolate-brown appearance. Certain medications or chemicals can also trigger elevated methemoglobin levels. MB converts iron within hemoglobin back to its functional state, thereby treating the condition. The most common clinical use of methylene blue is the treatment of methemoglobinemia, for which a physician may prescribe MB injections. (source)
6. Fungal Nail Infections
   Methylene blue can help combat fungal infections, much like bacterial infections. A 2014 study demonstrates that methylene blue combined with red LED light effectively treats "distal and lateral fungal nail infections" (onychomycosis). (source)
   Several groups should not use methylene blue, including:
7. Newborns: MB leads to numerous adverse effects in newborns that are not observed in adults. Newborns must not receive MB.
8. Pregnant women: There is evidence that MB can cause fetal death when administered to the mother during the second trimester of pregnancy. Incidental exposure to MB in the first trimester may cause less fetal harm.
9. Nursing mothers: Methylene blue likely passes into breast milk. There is insufficient evidence to confirm that MB is safe for infants, so breastfeeding mothers are advised not to take this risk.
10. Individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency: MB can cause hemolytic anemia in people with G6PD deficiency. Some researchers suggest that G6PD deficiency should be a contraindication for the use of methylene blue. MB must be used with caution in G6PD deficiency. People taking antidepressants should also avoid it, as the combination can dangerously elevate serotonin levels.

Use 1 to 5 drops daily in a glass of water.
Our 1% methylene blue solution is a versatile product of exceptionally high purity and quality, suitable for various scientific, medical, and technical applications.

The solution is carefully manufactured to meet the highest standards, delivering accurate results across various applications. Properties: 1% methylene blue solution composed of pure methylene blue and high-grade, ozone-purified water.

It is free from heavy metals, formaldehyde, solvent residues, nanoparticles, preservatives, genetic modification, and microbial contamination. Our methylene blue is produced and packaged in the Netherlands.

Applications: Microscopy: Ideal for staining cell nuclei and microorganisms in histological and microbiological preparations. Scientific research: Suitable for biochemical and cellular biology experiments.

Aquatics: For treating fungal infections and parasites in aquariums (use with care and follow instructions).